Christian R Engwerda Selected Research

Antiparasitic Agents (Antiparasitics)

12/2020	Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory.
1/2019	Innate Lymphocytes and Malaria - Players or Spectators?
1/2018	Early Changes in CD4+ T-Cell Activation During Blood-Stage Plasmodium falciparum Infection.
1/2018	Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection.
12/2016	The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria.
1/2015	Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection.
3/2010	Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity.

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Christian R Engwerda Research Topics

Disease

46	Infections 01/2022 - 05/2002
32	Malaria 01/2021 - 01/2005
10	Inflammation (Inflammations) 01/2022 - 04/2009
10	Visceral Leishmaniasis (Kala Azar) 10/2020 - 12/2004
7	Neoplasms (Cancer) 01/2022 - 03/2010
7	Cerebral Malaria 06/2011 - 05/2002
6	Parasitic Diseases (Parasitic Disease) 12/2018 - 01/2014
6	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2017 - 08/2007
4	Parasitemia 01/2017 - 08/2007
4	Communicable Diseases (Infectious Diseases) 01/2017 - 09/2008
3	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2022 - 04/2009
3	Hookworm Infections (Hookworm Infection) 12/2021 - 01/2011
3	Coinfection 05/2015 - 10/2004
2	Asymptomatic Infections 01/2022 - 01/2016
2	Cytokine Release Syndrome 01/2021 - 06/2012
2	Splenomegaly 12/2020 - 10/2004
2	Convalescence 01/2020 - 01/2017
2	Acute malaria 01/2020 - 06/2009
2	Granuloma 10/2016 - 12/2004
2	Weight Loss (Weight Reduction) 05/2015 - 01/2005
2	Persistent Infection 03/2010 - 02/2008
1	Melanoma (Melanoma, Malignant) 01/2022
1	Squamous Cell Carcinoma of Head and Neck 01/2022
1	Exanthema (Rash) 12/2021
1	COVID-19 01/2021
1	Chronic Disease (Chronic Diseases) 10/2020
1	Noncommunicable Diseases 01/2018
1	Leishmaniasis 01/2017
1	Dust Mite Allergy 10/2016
1	Asthma (Bronchial Asthma) 10/2016
1	Hypersensitivity (Allergy) 01/2016
1	Epstein-Barr Virus Infections 05/2015
1	Pneumovirus Infections 05/2015
1	Pneumonia (Pneumonitis) 05/2015
1	Lymphopenia (Lymphocytopenia) 04/2014
1	Opportunistic Infections (Opportunistic Infection) 06/2012

Drug/Important Bio-Agent (IBA)

19	CytokinesIBA 02/2021 - 08/2002
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2010
9	VaccinesIBA 12/2021 - 01/2005
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 05/2002
9	Interleukin-10 (Interleukin 10)IBA 01/2019 - 08/2007
7	Antiparasitic Agents (Antiparasitics)IBA 12/2020 - 03/2010
6	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2017
6	Pharmaceutical PreparationsIBA 01/2021 - 03/2010
6	AntibodiesIBA 12/2020 - 01/2005
6	HLA-DR Antigens (HLA-DR)IBA 01/2020 - 08/2015
6	AntigensIBA 01/2018 - 01/2005
5	Interferon Type IIBA 01/2020 - 09/2011
4	Antimalarials (Antimalarial Agents)IBA 12/2020 - 06/2009
4	Lymphotoxin-alpha (Lymphotoxin)IBA 10/2010 - 05/2002
3	Malaria VaccinesIBA 01/2018 - 02/2005
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 02/2016 - 04/2009
3	Interleukin-12 (IL 12)IBA 01/2016 - 10/2011
2	AmphiregulinIBA 01/2022 - 01/2022
2	LigandsIBA 01/2022 - 12/2008
2	InterferonsIBA 01/2020 - 01/2018
2	Immune Checkpoint InhibitorsIBA 01/2018 - 02/2016
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 04/2017
2	Immunoglobulin G (IgG)IBA 11/2016 - 06/2009
2	GlucocorticoidsIBA 02/2016 - 03/2010
2	chenodeoxycholate sulfate conjugate (CDCS)IBA 06/2014 - 06/2012
1	Small Cytoplasmic RNAIBA 01/2022
1	ruxolitinibIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Growth Factor ReceptorsIBA 01/2022
1	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2022
1	Albendazole (Albenza)FDA Link 12/2021
1	flt3 ligand protein (flt3 ligand)IBA 02/2021
1	apabetaloneIBA 01/2021
1	Interferon-gamma (Interferon, gamma)IBA 01/2021
1	InterleukinsIBA 01/2021
1	Poly I-CIBA 01/2021
1	SteroidsIBA 01/2021
1	Interleukin-27 (Interleukin 27)IBA 10/2020
1	Complement System Proteins (Complement)IBA 09/2019
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 01/2018
1	Immune Checkpoint ProteinsIBA 01/2018
1	Caspase 3 (Caspase-3)IBA 01/2017
1	Galectin 1 (LGALS1)IBA 01/2017
1	KynurenineIBA 01/2017
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2017
1	Immunoglobulin M (IgM)IBA 11/2016
1	Recombinant ProteinsIBA 10/2016
1	LipopolysaccharidesIBA 10/2016
1	Messenger RNA (mRNA)IBA 01/2016
1	Interleukin-2 (IL2)IBA 01/2016
1	Interleukin-17 (Interleukin 17)IBA 12/2015
1	Leishmaniasis VaccinesIBA 07/2015
1	Interferon-betaIBA 05/2015
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2014
1	Fingolimod Hydrochloride (FTY720)FDA Link 04/2014
1	Interleukin-22 (IL-22)IBA 02/2012

Therapy/Procedure

8	Therapeutics 10/2020 - 02/2008
4	Bone Marrow Transplantation (Transplantation, Bone Marrow) 04/2017 - 01/2010
3	Immunotherapy 01/2022 - 03/2010
3	Transplantation 06/2012 - 01/2009
2	Chemoprevention 12/2020 - 10/2016
1	Intraperitoneal Injections 01/2018
1	Stem Cell Transplantation 01/2016